According to Drugs.com, pantoprazole may affect the hematological system and lead to anemia, low white blood cells, decreased platelets and increased eosinophils.
According to Drugs.com, pantoprazole may affect the skin and cause acne, alopecia, contact dermatitis, dry skin, eczema, rash, itching and sweating.
High doses of pantoprazole may affect the eyes and cause double vision, cataracts, glaucoma and blurred vision, according to Drugs.com.
According to Drugs.com, excess pantoprazole in the bloodstream may affect the kidneys and bladder and lead to decreased urination, painful urination, blood in urine, kidney stones and kidney pain.
The U.S. Food and Drug Administration website states that long-term use of high dosages of pantoprazole may lead to bone fractures of the hip, wrist and spine. Pantoprazole may also cause arthritis, neck rigidity, bone pain and muscle pain.